SORD anticorps (AA 307-357)
Aperçu rapide pour SORD anticorps (AA 307-357) (ABIN7450756)
Antigène
Voir toutes SORD AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 307-357
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Fonction
- Rabbit anti-SORD Antibody, Affinity Purified
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Purification
- Affinity Purified
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Immunogène
- between AA 307 and 357
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Isotype
- IgG
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Indications d'application
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IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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Restrictions
- For Research Use only
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Concentration
- 200 μg/mL
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Buffer
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Date de péremption
- 12 months
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- SORD (Sorbitol Dehydrogenase (SORD))
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Autre désignation
- SORD
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Sujet
- Background: Sorbitol dehydrogenase (SORD) catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase, makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications (summarized by Carr and Markham, 1995 [PubMed 8535074]). The first reaction of the pathway (also called the polyol pathway) is the reduction of glucose to sorbitol by ALDR1 with NADPH as the cofactor. SORD then oxidizes the sorbitol to fructose using NAD(+) cofactor [taken from NCBI Entrez Gene (Gene ID: 6652)].
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ID gène
- 6652
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NCBI Accession
- NP_003095
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UniProt
- Q00796
Antigène
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